Estimating the atherogenic risk in patients with chronic kidney disease: a complementary evaluation in cardiovascular risk

Section: Originals

How to quote

Fürstenheim Milerud LP, Amat Camats G, Vilela Pájaro A, García Serrano C. Cálculo del riesgo aterogénico en pacientes con enfermedad renal crónica. Una valoración complementaria en el riesgo cardiovascular. Metas Enferm sep 2020; 23(7):16-23. https://doi.org/10.35667/MetasEnf.2020.23.1003081626

Authors

Laura Paloma Fürstenheim Milerud1, Gemma Amat Camats2, Álvaro Vilela Pájaro3, Cristina García Serrano1

Position

1Enfermera Especialista en Enfermería Familiar y Comunitaria. ABS Balaguer (Lleida) 2Enfermera Máster Oficial en Ciencias de la Enfermería. ABS Balaguer (Lleida) 3Enfermero Especialista en Enfermería Familiar y Comunitaria. CAP Onze de Setembre (Lleida)

Contact address

Laura Paloma Fürstenheim Milerud. C/ Portal del Segre, 6. 25613 Camarasa (Lleida).

Contact email: lfurstenheim@gmail.com

Abstract

Objective: to determine the atherogenic risk in patients with chronic kidney disease (CKD), as well as to explore the influence of gender and diabetes mellitus (DM) in said risk.
Method: a descriptive cross-sectional study in CKD patients from the Balaguer Basic Health Area (n= 1.852). Variables analyzed: gender, DM, HDLc-LDLc-triglycerides (TGc)-total cholesterol (TC); indexes: TC/HDLc, LDLc/HDLc, TG/HDLc, No-HDLc. Statistical analysis through Chi square-Mann-Whitney U with the SPSS program.
Results: in total, 1,834 patients met the inclusion criteria. Optimal values of lipid control were observed (62.6% with TC< 200 mg/dl), though there was a high prevalence of elevated AR (73.3% according to the TC/HDLc ratio). Women (with or without DM) presented higher lipid values than men: TC 190 mg/dL (SD: 41.3) with DM and 198 mg/dl (SD: 39.1) without DM, vs. 175 mg/dl (SD: 37.2) with DM and 183 mg/dl (SD: 38.9) without DM (p< 0.001). The estimation of AR for women was superior in all ratios except for TGc/HDLc. Non-diabetic persons presented a higher prevalence of high AR vs. diabetic persons; it was higher in LDLc/HDLc (44.4% without DM vs. 39.8% with DM), and No-HDLc (68.0% without DM vs. 59.3% with DM), but lower in TGc/HDLc (57.7% without DM vs. 76.6% with DM) and TC/HDLc (72.7% without DM vs. 74.4% with DM).
Conclusions: it seems that both AR values and lipid control (TC, LDLc) are better in persons with DM (potential treatment intensity), and worse in women. No-HDLc stands out as the best predictor among all indexes for calculating AR.

Keywords:

dyslipidemia; hypercholesterolemia; HDL-cholesterol; LDL-cholesterol; renal failure; tertiary prevention; advanced practice nursing; cardiovascular conditions; descriptive cross-sectional studies

Versión en Español

Título:

Cálculo del riesgo aterogénico en pacientes con enfermedad renal crónica. Una valoración complementaria en el riesgo cardiovascular