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Metas de Enfermería

Metas de Enfermería

MARZO 2006 N° 2 Volumen 9

Sillybum marianum

Section: Medicinal herbs

How to quote

González Sanguino C, Serrano Ruiz A. Sillybum marianum. Metas de Enferm mar 2006; 9(2): 50-52

Authors

1Cristina González Sanguino, 2Alfredo Serrano Ruiz

Position

1Enfermera. Servicio de Hematología. Hospital Severo Ochoa. 2Enfermero. Servicio de Farmacología Clínica. Hospital Puerta de Hierro (Madrid).

Contact address

Servicio de Farmacología Clínica. Hospital Puerta de Hierro. C/ San Martín de Porres, 4. 28035 Madrid.

Contact email: aserrano.hpth@salud.madrid.org

Abstract

A plant called sillybum marianum has been used in Europe since the IV century BC for the treatment of hepatic disorders, animal bites and intoxications. At present, we know that the active molecule is a flavonoid called silimarine used, besides this classical indications, for its cytoprotector effect on the ageing process and the molecular mechanisms that cause cell damaged mediated by inflammatory response-related agents
There is no evidence showing a beneficial effect on liver disorders (hepatitis, cirrhosis, etc.).
The consumption of sillybum marianum causes in some cases mild gastrointestinal alterations. No drug interactions have been described.

Keywords:

sillybum marianum; silimarine; cytoprotector; antioxidant; epatic disorders; medicinal plantspharmacology

Versión en Español

Título:

Sillybum marianum