Metas de Enfermería

Metas de Enfermería

SEPTIEMBRE 2006 N° 7 Volumen 9

Permeabilisation of peripheral venous catheters of intermittent use: with and without heparin

Section: Method

How to quote

Lacasaña Bellmunt P, García Ortega MJ, García Ruiz C, Palomino Gutiérrez B, Toro Padilla R, Cánovas Galera P et al. Permeabilización de catéteres venosos periféricos de uso intermitente: con y sin heparina. Metas de Enferm sep 2006; 9(7): 10-16


1Pedro Lacasaña Bellmunt1, 1Mª José García Ortega, 1Carolina García Ruiz, 1Belén Palomino Gutiérrez, Reyes Toro Padilla, 1Ana Vila Sánchez, 2Providencia Cánovas Galera, 1Rosa Canals Tur


1Enfermero/a Asistencial Hospital Can Misses (Ib-Salut) Ibiza, Servei Balear de Salut.2Supervisora Hospitalización Hospital Can Misses (Ib-Salut) Ibiza, Servei Balear de Salut.

Contact address

C/ Avestruz, 13. 07819 Jesús, Ibiza (Baleares).

Contact email: lacasana@telefonica.net


Some studies suggest that the use of sodium heparin (HepNa) for permeabilisation of venous catheters of intermittent use does not present any higher effectiveness in the prevention of occlusions or phlebitis than 0,9% pure ClNa. Even though it is generally used, we are yet unclear on whether it is really effective and on what the necessary dose of HepNa is. The objective of the study was to determine the efficacy of HepNa at a concentration of 100 U.I./ml compared to the use of 0,9% pure ClNa, comparing the incidence of occlusion and phlebitis with both regimens. An experimental, randomised, double blind study was designed. Two groups were created. One group was permeabilised with HepNa, “control group” or method A; the other group was called the “intervention group” or method B and was permeabilised using 0,9% ClNa.The sample size was 235 and data from a total of 383 peripheral catheters was collected.
There were 17 occlusions (4,43%), 6/190 method A (3,15%) and 11/193 method B (5,69%), with no significant difference (p=0,227). Phlebitis developed in 72 cases (18,79%), 27/190 method A (14,21%) and 45/193 method B (23,31%), with a significant difference (p=0,023) between both methods.
Based on a review of the literature and on our own results, we are able to conclude that the dose of heparin necessary to show a benefit and decrease phlebitis would have to be higher than 10 UI/ml and that with 100 UI/ml provides an evident benefit.


peripheral catheter; catheter permeabilisation; catheter occlusion; Phlebitiscare techniques

Versión en Español


Permeabilización de catéteres venosos periféricos de uso intermitente: con y sin heparina