Vitamin D supplements and risk of preeclampsia in pregnant women
Section: Revisions
How to quote
Jiménez Siles S, Oropesa Ropero J. Suplementación de vitamina D en mujeres embarazadas y riesgo de preeclampsia. Matronas Hoy 2020; 9(1):29-36.
Authors
1 Sara Jiménez Siles, 2 Juan Oropesa Ropero
Position
1 Matrona AP. OSI Bilbao-Basurto. Vizcaya.2 Matrón. Hospital General Universitario San Jorge. Huesca.
Contact email: Sara51295@hotmail.es
Abstract
Introduction: vitamin D deficiency in pregnant women has been associated with an increased risk of preeclampsia. However, efficacy and benefits of vitamin D supplements continue to be controversial. A literature review was carried out to evaluate the impact of vitamin D supplements in pregnant women.
Purpose: to establish whether vitamin D supplements in pregnant women have an impact on the risk of preeclampsia and gestational diabetes in pregnancy.
Methods: a literature review was performed. An initial search was carried out in several databases which resulted in 23 articles being selected based on the inclusion and exclusion criteria. A critical reading was carried out, leading to a final selection of seven systematic reviews.
Results: most of the seven systematic reviews included showed that vitamin D supplementing during pregnancy probably reduced the risk of preeclampsia and gestational diabetes. Vitamin D supplements did not cause important adverse effects and had no adverse impact on the development of the pregnancy or on the fetus.
Discussion: study designs are very heterogeneous, but the evidence seems to lean towards a protective effect in women receiving vitamin D supplements.
Conclusion: although vitamin D supplements seem to reduce the risks of preeclampsia or gestational diabetes, current data should be interpreted with caution, since the available information is limited due to the heterogeneity of the studies, the variety of doses used in the studies, the multiple variables that can affect the absorption and metabolism of vitamin D, and the non-significant results. Therefore, further research is suggested.
Keywords:
vitamin D; preeclampsiaprimary prevention
Versión en Español
Título:
Suplementación de vitamina D en mujeres embarazadas y riesgo de preeclampsia
Artículo completo no disponible en este idioma / Full article is not available in this language
Bibliography
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