Severe hypoglycaemia secondary to IV pentamidine in a woman receiving an allogeneic stem cell transplant
Section: Práctica Clínica
How to quote
López Moreno JM, Cabrera Jaime S, Sánchez Migallón JM, Jiménez Zárate AM, Comabella Pobes R. Hipoglucemia secundaria a pentamidina intravenosa en mujer receptora de un trasplante alogénico de progenitores hematopoyéticos. Metas Enferm may 2016; 19(4): 28-32.
Authors
José Manuel López Moreno1, Sandra Cabrera Jaime2, José Manuel Sánchez Migallón3,Ana María Jiménez Zárate4, Rosa Comabella Pobes5
Position
1Enfermero clínico. Unidad de Hospitalización Onco-hematológica. Institut Català d’Oncologia. Badalona (Barcelona)2Doctora en Ciencias Enfermeras. Institut Català d’Oncologia. GRIN Group IDIBELL, Institute of Biomedical Research. Hospitalet (Barcelona)3Dietista-Nutricionista. Institut Català d’Oncologia. Badalona (Barcelona)4Responsable de Enfermería Unidad de Hospitalización Onco-hematológica. Institut Català d’Oncologia. Badalona (Barcelona)5Adjunta Dirección de Cuidados. Institut Català d’Oncologia. Badalona (Barcelona)
Contact address
José Manuel López Moreno. Institut Català d’Oncologia. Badalona. Unidad Hospitalización de Onco-hematología. Carretera de Canyet, s/n. 08916 Badalona
Contact email: jmlopez@iconcologia.net
Abstract
Those patients receiving a stem cell transplant (SCT) as treatment will present a particular tendency to develop infections. The most frequent pathogens are Candida and Aspergillus, which entail a high morbimortality rate. The treatment of choice for infection by Pneumocystis Jiroveci is Trimethoprim/sulfamethoxazole (TMP/SMX).
Lack of tolerability to TMP-SMX or myelosuppression, which is a common situation among patients receiving a SCT, will sometimes require the use of pentamidine. During its administration, either intravenous or inhaled, glucose levels must be monitored, because there have been reports about alterations of the levels of glucose in blood. There are few patients who require a prescription of intravenous pentamidine, but due to the high risk of severe hypoglycaemia, its administration requires a specific protocol of care. The objective of the present clinical case is to create awareness about the protocol for hyperfractionated diet in patients undergoing stem cell transplant, during treatment with said drug.
Keywords:
Allogeneic transplant; hypoglycaemia; pentamidinehyperfractionated diet
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