Authors

Francisco Javier García Sánchez1, Almudena Nieto Ramos2, Natalia Mudarra García1

Position

1 Doctor/a por la Universidad Complutense de Madrid (UCM). Unidad de Prehabilitación Quirúrgica. Hospital Universitario Infanta Cristina. Departamento de Medicina. Facultad de Medicina. UCM. IDIPHISA. Madrid (España)2 Enfermera. Consulta de Prehabilitación Quirúrgica. Hospital Universitario Infanta Cristina. Parla, Madrid (España)

Contact address

Natalia Mudarra García. C/ Esperanza, 26. 28609 Sevilla La Nueva, Madrid (España).

Contact email: nmudarra@enf.ucm.es

Abstract

Objectives: to understand the differences in surgical results in patients with preoperative anemia treated with Ferric carboxymaltose (FCM) or without iron before surgery.
Methods: a retrospective observational study of two patient cohorts: a Group without preoperative FCM (before the implementation of the Surgical Prehabilitation program), and a Group with FCM (after the implementation of the program). A review of electronic clinical records; the outcome variables were the number of transfusions of blood products required after surgery, postsurgical complications, and days of hospital stay. There was a comparison of study variables through Chi square and Student’s t tests; the SPSS statistical program, v. 26, was used.
Results: the study included 152 patients, 92 in the FCM Group (2020-2022) and 56 in the Group without FCM (2019); 60.5% (n= 92) were female. Their mean age (standard deviation) was 63.91 (13) years. The surgical procedures included were: colectomy (n= 77; 64.5%), mastectomy (n= 55; 23%) and hysterectomy (n= 20; 12.5%). Statistically significant outcomes were found between the need for blood transfusions (p< 0.001; OR 15.91 (4.44-57.01)), postsurgical complications (p< 0.001; OR 7.36 (3.35-16.16)), and the mean hospital stay (p< 0.001), which was 4.14 days in the FCM group vs. nine days in the control group without FCM.
Conclusions: treatment with FCM reduced the number of blood transfusions, postsurgical complications, and days of hospital stay.

Keywords:

Iron deficiency; anemia; hemolytic; iron-deficiency; prehabilitation; surgery

Versión en Español

Título:

Diferencias en los resultados quirúrgicos en pacientes con anemia preoperatoria tratada con hierro o sin hierro previo a la cirugía