Acellular fish skin grafts in the treatment of diabetic foot ulcers. Literature review

Section: Reviews

How to quote

Sánchez Lozano J, Martínez Pizarro S. Injertos de piel de pescado acelular en el tratamiento de las úlceras de pie diabético. Revisión de la literatura. Rev. iberoam. Educ. investi. Enferm. 2024; 14(1):e9. doi: https://doi.org/10.56104/Aladafe.2024.14.1021000435

Authors

1 Jesús Sánchez Lozano, 2 Sandra Martínez Pizarro

Position

1 Graduado en Fisioterapia por la Universidad Católica San Antonio de Murcia (UCAM). Clínica de fisioterapia Fisalde. ORCID: https://orcid.org/0009-0003-7595-57332 Graduada en Enfermería por la Universidad de Granada (UGR). Servicio Andaluz de Salud. Dispositivo apoyo Nordeste de Granada. ORCID: https://orcid.org/0000-0003-3070-8299

Contact email: mpsandrita@hotmail.com

Abstract

Introduction: diabetic foot ulcers are a serious complication of diabetes that is associated with increased morbidity and mortality, as well as a substantial economic burden. The treatment is complex, which is why complementary therapies are being studied for ulcers that are difficult to heal. Recently, acellular fish skin grafts have been suggested. Fish skin has demonstrated anti-inflammatory and antibacterial properties that promote and improve wound healing. The objective of this work is to conduct a review on the effectiveness of acellular fish skin grafts in diabetic foot ulcers.
Method: a review was carried out following the PRISMA regulations. The databases of PubMed, Cinahl, PsycINFO, SPORTDiscus, Academic Search Complete, Lilacs, IBECS, CENTRAL, SciELO and WOS were consulted. The Cochrane tool was used to assess the risk of bias.
Results: acellular fish skin graft is effective in reducing healing time in diabetic foot ulcers. The total sample was 327 patients from six studies. The duration of treatment ranged from 6 to 16 weeks. All studies showed safety.
Conclusions: fish skin graft promotes ulcer healing, especially during the first four weeks. Additionally, this treatment generates lower costs, along with greater wound healing than standard treatment.

Versión en Español

Título:

Injertos de piel de pescado acelular en el tratamiento de las úlceras de pie diabético. Revisión de la literatura

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